I know it doesn't allow voice recording, but a high quality paint mask would allow you to breathe for extended periods of time while using the computer and wearing glasses.
I use one like this all the time, sometimes for hours at a time. Don't over tighten the straps, as it can make it press against the bridge of your nose and will get sore over time. The "organic vapor cartridges", which is the pair of filters on the sides of your face when wearing it, are pretty amazing. Don't be tempted by the cheaper, round pink filters... pretty useless against anything smaller than saw dust (which mold spores are). The one annoyance I have is that condensation inside the mask sometimes drips out... keep a towel on your lap, and don't lean over the keyboard too much.
If you can find a pair of these locally at a hardware or painting supply store, you and your wife will at least be able to work and relax without the constant distraction of bad smells.
I would also like to support the use of dehumidifiers, even if they are expensive to run. Mold hates being dry, and loves being moist.
Best of luck!